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The Department of Cell Biology focuses on research of the molecular structure and function of cells and their component parts with a vision of determining how cells interact to form embryos, tissues, and nervous systems, as well as investigating their role in physiology, behavior, and tissue repair and regeneration. Contains teaching notes relating to cell and tissue biology and microanatomy. Types of materials include class schedules, lecture notes, slide list, lab assignments, and study questions. Materials date to 1989.

Pastoral services are available at all Duke Health hospitals any time of day or night. The chaplaincy program at Duke Hospital was started by P. Wesley Aitken shortly after Aikten's graduation from Duke Divinity School in July 1956. Contains a portrait of P. Wesley Aitken. Portrait is undated.

Contains the administrative records of the Department of Family Medicine and Community Health, formerly named the Department of Community and Family Medicine (1979-2019). Prior to 1979, the department was the Department of Community Health Science. This collection contains correspondence, reports, budgets, minutes, writings, planning materials, news releases, clippings, rosters, course and curriculum materials, residency and internship materials, evaluations, surveys, committee materials, field reports, award information, artwork, photographic materials, AV materials, and digital files. Photographs include Mead Johnson Award winners, 1981-1988; Duke-Watts Family Medicine Faculty and Residents, 1973-1993; Duke Family Medicine Program group photographs, 1983-1995; staff photographs (both identified and unidentified); staff parties and events; and Duke Endowment-King's Fund College, 1971-1981. Images also include departmental faculty members including E. Harvey Estes, Jr.; Samuel W. Warburton; and Kathryn M. Andolsek. Major topics include the Family Medicine Residency Program, the Division of Family Medicine, Student Health, the Regional Medical Program, the King's Fund, the Duke Endowment, Sea Level Hospital, the Andean Rural Health Project, the Fallout Preparedness Committee, and Medical Education for National Defense. Materials date from 1959 to 2021.

Materials relate to the history and administration of Duke's Department of Health Administration, established in 1930 as the first graduate program in the nation for the training of hospital administrators. Contains newsletters, correspondence, meeting minutes, attendance and membership lists, reports, articles, studies, notes, course evaluations, agendas, bound oral history transcripts, curriculum vitae, financial records, invoices, event programs, program applications, course catalogs, and photographs. Materials range in date from 1943 to 1991.

The Department of Medicine was established in 1930, coinciding with the opening of Duke Hospital. Types of materials include reprints; appointment lists of professors, associates, instructors, residents, affiliates, and alumni; biographical sketches; Eugene A. Stead Jr. alumni lists; a biography of Frederic Moir Hanes; lists of chief residents of Duke Hospital, VA Medical Center, and Ambulatory Care; a list of the numbers of house staff; student, house staff, and faculty files; and staff and faculty group photographs. Major subjects include the Department of Medicine. Materials date from 1930 to 2017.

Contains bound copies of articles published by members of the Microbiology Department. Also includes a composite image from the Department of Molecular Genetics and Microbiology's seasonal door decorating contest with COVID-19 playing a prominent role. Materials range in date from 1931 to 2020.

The Department of Neurobiology was established in 1988. This collection contains handbooks, correspondence, curriculum brochures, meeting minutes, program proposals, curriculum vitae, portraits, and a committee report. Materials range in date from 1981 to 2001.

The Duke Department of Neurology works to advance understanding of the brain and nervous system, translate that understanding into treatment and prevention, and provide outstanding patient care. Contains posters presented at various conferences. Materials date from 2006 to 2018.

Duke Neurosurgery was created in 1937, although it did not become a department until July 1, 2015. Prior to becoming a department, Neurosurgery was a division under the Department of Surgery. Contains materials documenting Dr. Guy Odom and Dr. Blaine Nashold's work for Duke Neurosurgery. Types of materials include patient records, 16mm films documenting various conditions, departmental administrative records, photographs, lantern slides, surgical knives, and a Riechert Mundinger cerebral stereotaxy frame and some related surgical components. Materials dates from 1922 to 2023 with the bulk dating from 1922 to 1988.

The Department of Obstetrics and Gynecology was established in 1930 as one of the founding departments at Duke University Medical Center. This collection contains articles, clippings, order forms, lectures, survey results, slides, Roy T. Parker Symposium programs, correspondence, artifacts, plaques, printed materials, photographs, negatives, and delivery and procedure logs produced by Department of Obstetrics and Gynecology faculty members from 1930 to 1995. Major contributors include F. Bayard Carter, E. C. Hamblen, and Robert A. Ross. Materials range in date from 1930 to 2018.