The Duke Clinical Research Institute (DCRI) was created in 1996 from the Duke Databank for Cardiovascular Disease (DDCD). Dr. Robert M. Califf was named as the first DCRI director. The DCRI designs and conducts small and large multinational clinical trials. Contains correspondence, reports, newsletters, meeting agendas, research applications, clinical trial research reports, articles, presentations, meeting minutes, financial materials, pamphlets, brochures, audiovisual materials, and photographs. Materials range in date from 1983 to 2018.