Contains the professional papers of Edward S. Orgain (1906-1995), professor of medicine and founding director of the Cardiovascular Diseases Service at Duke University. Types of materials include correspondence, contracts, minutes, notes, agendas, newsletters, short writings, reprints, brochures, and photographs. Major subjects include Edward S. Orgain, the Duke University Private Diagnostic Clinic, and heart diseases. Materials range in date from 1938 to 1995.