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Contains Onyekwere Akwari's personal and professional correspondence. Materials are organized chronologically by correspondent, with individual files for major correspondents. Of note is the correspondence located in the "Stead, Eugene A." folder. These emails were given to Akwari by Dr. Louis (Lou) W. Sullivan. The letters document Dr. Stead's attempt to hire Sullivan to an Associate position in 1962-1963. This was denied by Duke University Provost R. Taylor Cole who would only approve Sullivan be hired to an Adjunct Associate position. Sullivan turned down the position and went on to become the President of Morehouse School of Medicine and US Secretary of Health and Human Services under President George H. W. Bush. These letters illustrate how racial, ethic, and gender minorities were historically described and evaluated. Materials date from 1961 to 2018.

Contains cassette tapes, CDs, DVDs, U-Matic video cassettes, and 16mm film containing audiovisual materials pertaining to Onyekwere Akwari's personal and professional life. The U-Matic video cassettes are believed to be from the inaugural meeting of the Society of Black American Surgeons (SBAS) in 1989. Materials date from 1974 to 2008, though the bulk is undated.

Contains funeral programs and obituaries collected by Onyekwere Akwari. Materials are organized by decade, with individual files dedicated to the deaths of Akwari family members and Dr. William Anlyan. Materials date from 1980 to 2019.