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The collection documents facilities planning and construction activities of the Duke University Medical Center. These materials also show the evolution of responsibility for health facilities planning and administration during a period of extensive building activity that occurred before the organization of the Facilities Planning, Design and Construction Office within the Medical Center and Health System Architect's Office. Included are records of major planning initiatives and specific building projects from the offices of Louis E. Swanson, an early director of the Medical Center Planning Office, and Dr. Jane G. Elchlepp, the first assistant dean for planning. In addition to correspondence, memoranda, committee minutes, statistical reports, and planning reference materials, the collection contains design studies and long-range planning proposals completed between 1952 and 1998. Presentation drawings and graphics span the years 1964 to 2000. The collection also contains photographs, slides, and other documentation pertaining to the planning and construction of Duke Hospital North from 1973 to 1980. Materials date from 1952 to 2013.

Contains the professional papers of Jane Elchlepp,member of the Department of Pathology and assistant vice president for health affairs, planning, and analysis. Types of materials include correspondence, reports, budgets, contracts, and committee materials. Major subjects include hospital planning and construction, Duke Hospital, and the Duke University Medical Center. Materials range in date from 1964 to 1991.

William George Anlyan (1925-2016) came to Duke University School of Medicine for his residency in general and thoracic surgery (1949-1955). Afterwards, he joined the surgical staff led by Dr. Deryl Hart, becoming a full professor of surgery in 1961, and, from 1964 to 1969, was the third dean of the School of Medicine. Anlyan also served as vice president for health affairs (1969-1983) and chancellor for health affairs (1983-1989). From 1988 to 1993, Anlyan was the executive vice president and cencellor for health affairs before becoming chancellor of Duke University (1990-1995). This collection contains 9 oral history interviews conducted in 1978, 1993, 1994, 1995, 1997, 2004, and 2007. Interviews in the 1990s were conducted by Dr. James Gifford. Interviews conducted in the 2000s were conducted by Jessica Roseberry.