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Contains news clippings pertaining to Duke University Medical Center. Major subjects include Duke University Hospital, Duke University School of Medicine, Duke University School of Nursing, Highland Hospital, and the 65th General Hospital. Clippings were collected by a news clipping service. Materials range in date from 1927 to 1986.

Contains photographs of the Duke University Medical Center (DUMC), staff, students, professors, departments, events and educational activities, class reunions, class photographs, and student life. Photographs of affiliated local hospitals such as Watts Hospital and Lincoln Hospital are also included. Also contains photographs appearing in the publications the Intercom (1979-1986) and Perspectives (1980-1991). Materials were created by various Duke University photographers, including staff from the Division of Educational Medial Services and Duke Photography; individuals; and the United States government. Types of materials include photographic prints of varying sizes, 35mm slides, film negatives of varying sizes, and digital files. Materials range in date from 1928 to 2024.

Contains manuals and records pertaining to the administration of Duke Hospital. Types of materials include autopsy records, instruction sheets, and Social Services Department Manual. Materials date to 1940, with the bulk undated.

Contains audio, video, and a small amount of digital photographs documenting the history of Duke University Medical Center. Coverage includes documentaries, alumni gatherings, interviews, speeches, lectures, conferences, awards, tributes, groundbreakings, building dedications, grand rounds, and student-faculty shows. Materials in this collection have been acquired from multiple sources. Some of the materials have been separated from existing collections. People featured in the collection include: Jay M. Arena; William G. Anlyan; Lenox D. Baker; Ivan W. Brown; F. Bayard Carter; Elon Clark; Martin M. Cummings; Wilburt C. Davison; Victor J. Dzau; Wiley D. Forbus; Joseph C. Greenfield, Jr.; Charles B. Hammond; Philip Handler; Merel Harmel; Barton F. Haynes; Leslie Hohman; Charles Johnson; Samuel L. Katz; Joseph E. Markee; Robert J. Reeves; David T. Smith; Eugene A. Stead, Jr.; Andrew G. Wallace; and Barnes Woodhall. Items of note include Wilburt C. Davison's Dave at Roaring Gap, MEDSAC and Quail Roost conference recordings, a 14-part orientation of Duke Hospital North, documentaries about the 65th General Hospital, documentaries about Duke's hyperbaric chamber, the multi-part interview series "Before the Colors Fade," and "Keepers of the House" documentary. Also includes videos of the School of Medicine's Match Day program and Memory Lane video series for graduating medical students. Types of formats include VHS tapes, Betacam tapes, U-Matic tapes, audiocassette tapes, DVDs, CDs, other forms for optical media, film, magnetic tapes, reel-to-reel audio, wire recordings, and digital files. Materials range in date from 1946 to 2024.