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Contains photographs of the Duke University Medical Center (DUMC), staff, students, professors, departments, events and educational activities, class reunions, class photographs, and student life. Photographs of affiliated local hospitals such as Watts Hospital and Lincoln Hospital are also included. Also contains photographs appearing in the publications the Intercom (1979-1986) and Perspectives (1980-1991). Materials were created by various Duke University photographers, including staff from the Division of Educational Medial Services and Duke Photography; individuals; and the United States government. Types of materials include photographic prints of varying sizes, 35mm slides, film negatives of varying sizes, and digital files. Materials range in date from 1928 to 2024.

James Buchanan Duke established the Duke Endowment in 1924. The endowment provided funds to form Duke's School of Medicine and Duke Hospital. Duke North opened in 1980 and was connected the older hospital, referred to as the South division, through a personnel rapid transit system (PRT). Types of materials include correspondence, meeting minutes, memoranda, floorplans, charts, reports, articles, notes, and surveys. Materials range in date from 1979 to 1982 but the bulk of the material is undated.

Contains the administrative files of the Office of Grants and Contracts within the Office of Research Administration at the Duke University School of Medicine. Types of materials include reports, research grants for the Department of Surgery, and budgets. Materials range in date from 1984 to 1993.

Duke University Medical Center's Transfusion Committee is responsible for ensuring the following of best practices and patient safety during blood utilization and transfusions. The Department of Anesthesiology in particular has played a key role in its operations. Contains correspondence and minutes for meetings related to the operation of the Medical Center's Transfusion Committee. Materials range in date from 1979 to 2002.

The Duke University Medical Center Board of Visitors is comprised of a combination of experts in the medical field and university trustees. The function of this board is to provide advice and support to the deans and senior faculty at Duke Medical Center. Materials range in date from 1964 to 1977.

Contains news clippings pertaining to Duke University Medical Center. Major subjects include Duke University Hospital, Duke University School of Medicine, Duke University School of Nursing, Highland Hospital, and the 65th General Hospital. Clippings were collected by a news clipping service. Materials range in date from 1927 to 1986.

James Buchanan Duke established the Duke Endowment in 1924. The endowment provided funds to form Duke's School of Medicine and Duke Hospital. Duke North opened in 1980 and was connected the older hospital, referred to as the South division, through a personnel rapid transit system (PRT). Construction of this addition corresponded to the construction of the hospital's nearby Communications Center and Medical Library, leading to a degree of overlap between records for both projects. Types of materials in this collection include meeting minutes, planning files, reports, construction notes, blueprints, conceptual drawings, correspondence, reference materials, accounting and revenue records, sound recordings, photographs, photographic slides, and negatives. Materials range in date from 1972 to 1986.

The collection documents facilities planning and construction activities of the Duke University Medical Center. These materials also show the evolution of responsibility for health facilities planning and administration during a period of extensive building activity that occurred before the organization of the Facilities Planning, Design and Construction Office within the Medical Center and Health System Architect's Office. Included are records of major planning initiatives and specific building projects from the offices of Louis E. Swanson, an early director of the Medical Center Planning Office, and Dr. Jane G. Elchlepp, the first assistant dean for planning. In addition to correspondence, memoranda, committee minutes, statistical reports, and planning reference materials, the collection contains design studies and long-range planning proposals completed between 1952 and 1998. Presentation drawings and graphics span the years 1964 to 2000. The collection also contains photographs, slides, and other documentation pertaining to the planning and construction of Duke Hospital North from 1973 to 1980. Materials date from 1952 to 2013.

Contains minutes for the annual faculty meetings for Duke University School of Medicine, which have traditionally been held in the spring of each academic year. Major topics include academic affairs at the Medical Center, yearly programs, and contemporary issues relevant to the Medical Center. Materials range in date from 1965 to 1994.