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Contains Harris' personal and professional materials from his medical education and career at Duke. Types of materials include artifacts, reprints, research materials, certificates, photographs, slides, unidentified 16mm film reels, mini cassette tapes, printed materials, correspondence, reports, notes, drafts, clippings, and other administrative materials. The series also contains artifacts used in pediatric developmental testing and monitoring, including a rattle, a spoon, plastic rings, bells, and a reflex hammer. Materials date to 1931 to 2003.

Contains Harris' professional materials from his time working at Duke. Types of materials include photographs, negatives, contact prints; IRB materials, both analog and digital; "Protection of Human Subjects in Research at DUMC" manual drafts and different versions; and other administrative materials. Materials date to 1934 to 2007.

Contains Harris' professional papers. Includes certificates, a plaque, photographs, writings, an unidentified pediatrics sound recording (reel-to-reel audio tape), correspondence, artwork, IRB materials, reprints, printed materials, clippings, and his retirement gift card. Materials date to 1938 to 2016.