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Contains programs, clippings, photographs, and programs. Materials range in date from 1930 to 1985.

Contains speaking notes, agendas, correspondence, and programs pertaining to the Orgain Symposium and various other professional conferences in which Orgain participated. Materials range in date from 1938 to 1995.

During the 1970s and 1980s, Orgain's research interests included the diagnosis and treatment of endocarditis, the diagnosis and pharmacological treatment of arrhythmias and congestive heart failure, and the investigation and pharmacological therapy of hypertensive vascular disease and of coronary artery disease. Contains newsletters, lists, memoranda, and financial materials pertaining to the Cardiovascular Diseases Service and the Cardiovascular Diseases Research Fund at Duke University. Materials range in date from 1946 to 1989.