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Contains articles, patient summaries, tests, discussion notes, informational materials relating to poisons and drug interactions, reports, and copies of newspaper clippings. Materials range in date from 1974 to 1987.

Contains internal forms used to track requests for information and phone calls to the Duke Poison Control Center. The forms include general information about the patient and poison, but now include an area to record the type of container, whether it was closed or open, and what kind of cautionary label was present. Materials date to 1987.

Contains materials, created by Duke Poison Control Center's first director, Jay Arena, toxicologist and pediatrician. Also includes research materials and correspondence concerning the development of the first child safety cap. Types of materials include correspondence, short writings, histories, brochures, pamphlets, posters, statistics, and reports. Materials range in date from 1951 to 1976.

Shirley K. Osterhout worked as a consultant to the Gastrointestinal Drugs Advisory Committee of the Bureau of Drugs of the Food and Drug Administration. The Committee was charged with reviewing the safety and effectiveness of prescription drugs. Osterhout served as a liaison between the consumer and medical community, representing the consumer's concerns in matters of gastrointestinal diseases. Types of materials in this series include correspondence, minutes, reports, and memoranda. Materials range in date from 1980 to 1983.