Contains the professional papers of David Tillerson Smith (1898-1981), James B. Duke Professor of Microbiology and chair of the Department of Microbiology (1930-1958) and associate professor of Medicine in the Department of Preventive Medicine (1950-1966) at Duke University. Types of materials include correspondence with individuals and organizations, research notes, clippings, article reprints, and manuscript materials. Major subjects include the Duke University School of Medicine, Department of Microbiology and Immunology, Department of Preventive Medicine, Turdeau Sanatarium, the research and teaching of microbiology, tuberculosis, pellagra, mycology, and bacteriology. Materials range in date from 1920 to 1970.