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This subseries includes a history of the unit and photographs of one of the unit's hospitals. Materials date from 1917 to 1959.

This subseries includes correspondence, unit reports, hospital regulations, and newsletters. Also contains a separate historical report of the Nursing Service and a summary by chief surgical officer Clarence Gardner of his work. Materials date from 1942 to 1953.

Materials include a complete record of patient admissions, dispositions, deaths, and clinical abstracts of severely wounded men. One is for George Buske, a case later publicized by Ivan Brown. Also contains extensive clinical study data on the early use of penicillin in treating syphilis. Materials date from 1944 to 1945.

This subseries contains photographs of the units work and leisure activities, as well as some graphic pictures of severe wounds. There are additional photographs in the Norman Ross Papers Series and the O. Norris Smith Papers Series. Materials range in date from circa 1942 to 1946.

This series includes postcards, a map, and sketches. Also contains work by British artist Frank A. Beresford. Beresford, a soldier, was treated by members of the 65th General Hospital. He later created several paintings and prints of their activities. Materials range in date from circa 1944 to 1959.