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Contains professional papers of Robert J. Lefkowitz, James B. Duke Professor of Medicine and Biochemistry and Howard Hughes Medical Institute Investigator in the Department of Biochemistry at Duke University Medical Center. Types of materials include travel and conference materials, speeches, memoranda, committee materials, awards and honors, former employee files, old equipment files, grant materials, alumni files, material transfer agreements, mice invoices, research, and digital files. Major subjects include Duke University Department of Biochemistry, Duke University School of Medicine, and the Howard Hughes Medical Institute. Materials range in date from 1962 to 2023.

Contains the professional papers of Robert (Bob) L. Blake, Coordinator of the Department of Medical Illustration in the Duke University School of Medicine. Types of materials include pen and ink drawings, pencil sketches, watercolors, illustrations of various sizes, plates, programs, clippings, pamphlets, brochures, cards, photographic materials, and commercially published works. Major subjects include Duke University School of Medicine, Civilian Public Service Unit No. 61, conscientious objectors during World War II, and medical illustration. Materials range in date from 1940 to 1988.

Contains the professional papers of Robert L. Hill (1928-2012), professor and chairman of the Department of Biochemistry at Duke University Medical School. Types of materials include correspondence, reports, reprints, minutes, proposals, brochures, clippings, handwritten notes, budgets, contracts, drafts, and CVs. Major subjects include the American Societies of Experimental Biology (FASEB), the American Society for Biological Chemists (ASBC), Duke Program to Strengthen Medical Science Education (PSME), and the Whitehead Institute for Biomedical Research. Materials date from 1971 to 1983.

Contains the professional papers of Robert Martin Biddle (1913-2000), medical student and resident at Duke Medical School and Hospital from 1935 to 1943. Types of materials include printed materials and clinical notes from Biddle's time at Duke and Union Memorial Hospital in Baltimore, Maryland. Materials date from 1924 to 1941.

Robert M. Califf attended Duke University School of Medicine, and he completed his residency in internal medicine at University of California-San Francisco and a fellowship at Duke in cardiology. His early faculty appointments at Duke corresponded with his time as Director of the Cardiac Care Unit. Califf spent the majority of his career at Duke University. Most recently, he was Vice Chancellor for Health Data Science; Donald F. Fortin, MD Professor of Cardiology; and Director, Duke Forge. Under the Obama administration, he served as Deputy Commissioner for Medical Products and Tobacco at the Food and Drug Administration (FDA) (2015-2016), and was Commissioner of Food and Drugs (2016 to 2017). In November 2019, he left Duke for Alphabet. Califf is a prolific researcher in the areas of improving health outcomes, cardiovascular medicine, quality of care, and the clinical research enterprise. Califf is also pioneer of clinical trial research methods, and solidified infrastructure for clinical trials at Duke by founding the Duke Clinical Research Institute. This collection contains 2 oral history interviews conducted at separate times. Interviews were conducted on June 11, 2007 by Jessica Roseberry and October 18, 2019 by Josephine McRobbie. In the 2007 interview, Califf discusses how he entered the field of cardiology, medical school experiences, his career at Duke, and the evolution of the cardiology databank into the Duke Clinical Research Institute (DCRI). In the 2019 interview, Califf discusses his upbringing in South Carolina; his formation as a cardiologist; his work as a clinician, researcher, and administrator at Duke; and his 2016-2017 tenure as Commissioner of the Food and Drug Administration. Major topics include advances in cardiology, developments in clinical trial research, leadership, and mentorship.