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Contains bound copies of articles published by members of the Microbiology Department. Also includes a composite image from the Department of Molecular Genetics and Microbiology's seasonal door decorating contest with COVID-19 playing a prominent role. Materials range in date from 1931 to 2020.

The Department of Neurobiology was established in 1988. This collection contains handbooks, correspondence, curriculum brochures, meeting minutes, program proposals, curriculum vitae, portraits, and a committee report. Materials range in date from 1981 to 2001.

The Duke Department of Neurology works to advance understanding of the brain and nervous system, translate that understanding into treatment and prevention, and provide outstanding patient care. Contains posters presented at various conferences. Materials date from 2006 to 2018.

Duke Neurosurgery was created in 1937, although it did not become a department until July 1, 2015. Prior to becoming a department, Neurosurgery was a division under the Department of Surgery. Contains materials documenting Dr. Guy Odom and Dr. Blaine Nashold's work for Duke Neurosurgery. Types of materials include patient records, 16mm films documenting various conditions, departmental administrative records, photographs, lantern slides, surgical knives, and a Riechert Mundinger cerebral stereotaxy frame and some related surgical components. Materials dates from 1922 to 2023 with the bulk dating from 1922 to 1988.

The Department of Obstetrics and Gynecology was established in 1930 as one of the founding departments at Duke University Medical Center. This collection contains articles, clippings, order forms, lectures, survey results, slides, Roy T. Parker Symposium programs, correspondence, artifacts, plaques, printed materials, photographs, negatives, and delivery and procedure logs produced by Department of Obstetrics and Gynecology faculty members from 1930 to 1995. Major contributors include F. Bayard Carter, E. C. Hamblen, and Robert A. Ross. Materials range in date from 1930 to 2018.

The Department of Ophthalmology, established in 1965, began in 1930 as a division within the Department of Surgery. Divisions of the department include Comprehensive Ophthalmology, Cornea Service, Glaucoma, Neuro-Ophthalmology, Oculoplastics, Pediatric Ophthalmology, Research Division, and Vitreoretinal Service. This collection contains publications, administrative and departmental records, reprints by faculty and staff, research files and materials, alumni files, grant information, photographs, slides, negatives, audiovisual materials, and public relations materials. The materials date from 1940 to 2014. Materials range in date from 1940 to 2014.

Duke School of Medicine's Department of Pediatrics was founded in 1927 by Wilburt C. Davison, MD, the first dean of the medical school. He also served as the first Department of Pediatrics chair (1927 to 1954). Other chairs include Jerome Harris, MD; Samuel L. Katz, MD; Michael M. Frank, MD; Joseph St. Geme, MD; and Ann M. Reed, MD. The collection documents the Department of Pediatrics with information about the department, Duke Children's Hospital, and affiliated clinics. Types of materials include departmental administrative files, financial information, planning and development materials, Duke Children's Hospital blueprints, meeting and committee materials, research files, printed materials, correspondence, reports and manuals, a small amount of audiovisual materials, grant and award information, and a list of Pediatrics House Staff. Materials date from 1930 to 2014.

The Department of Physical Therapy at Duke University was established by Helen Kaiser in 1943. In 1970, the program began awarding a Master of Science degree. In 2000, the department transferred from offering a master's degree to offering a Doctor of Physical Therapy degree. The collection contains photographs, faculty-student picnic invitations, anniversary buttons, and graduation programs. The photographs include images of students, facilities, and faculty, including Helen Kaiser. The buttons are from the 50th (1993) and 60th (2003) anniversaries of the program. Materials range in date from 1942 to 2006.

The Department of Psychiatry & Behavioral Sciences, established in 1994, focuses on understanding the brain and mind through research, clinical care, and education with the goal to help people with mental health challenges live their best life. Prior to this, the department originated as the Division of Neuropsychiatry in the Department of Medicine in 1933. In 1940 it became the Department of Neuropsychiatry, and in 1951 the name changed to the Department of Psychiatry. Contains administrative records of the Department of Psychiatry and the Department of Psychiatry & Behavioral Sciences, as well as a small amount of portraits and scrapbooks. Materials range in date from 1944 to 1992.

In 1929, Dr. Robert James Reeves was appointed Instructor of Radiology and helped form the Department of Radiology at Duke. The first radioisotope laboratory at Duke was established in 1952.The Radiation and Oncology division formed in 1978, becoming a separate department in 1989, and the Nuclear Medicine division formed in 1979. Contains staff lists, meeting minutes, correspondence, graphs, clippings, notes, speeches, brochure, newsletters, programs, slides, and photographs. Materials range in date from 1932 to 1988.