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Dr. Joseph Odell Moore, MD, an oncologist, has worked within the Duke University Medical Center system for 45 years, first as an internal medicine fellow and finally as Professor of Medicine in the Department of Medicine. As a specialist in hematologic malignancies, he focuses on the understanding and treatment of cancers such as leukemia and lymphoma. His many achievements include advancing clinical research on myeloid leukemias and serving as a founding board member of the Jimmy V Foundation for Cancer Research. This collection contains 2 oral history interviews conducted on November 6 and 9 2020 by Joseph O'Connell as part of the Department of Medicine's Oral History Project. In the interviews, Moore discusses the advent of the specialization of hematologic oncology, Moore's early experiences that inspired his interest in medicine as a career, changes in Duke's facilities and programs over his tenure, and developments in cancer treatment. The themes of these interviews include medical training, the history of Duke Medical Center, and hematologic oncology.