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Dr. Jack Hughes, MD, served the Durham, North Carolina community in private urological practice from 1950 until his retirement in 1988. His work bridged his specialty in urological surgery with an interest in the medical science of stone disease. His clinical practice, research, and service to medical societies often involved collaborating with colleagues in academic medicine, especially at Duke University and the University of North Carolina at Chapel Hill. This collection contains 1 oral history interview conducted on October 3 and 4, 2019 by Joseph O'Connell. The October 3 and 4, 2019 interview with Hughes moves more or less chronologically through Hughes' upbringing and education, his military service during World War II, his residency and training in Minnesota, and his experiences at the intersection of academic and private practice medical communities in Durham, North Carolina.